Benzoyl Chlorides Pharma Agro
2-Fluorobenzoyl chloride is a colorless transparent liquid, an important fluorinated aromatic acyl chloride intermediate widely used in pharmaceuticals, pesticides, and fine chemicals. It has a melting point of 4℃, a boiling point of 95℃ (20 mmHg), hydrolyzes vigorously on contact with water, and requires sealed storage.
The distinctive feature of 2-fluorobenzoyl chloride lies in the dual role of the ortho fluorine: the strong electron-withdrawing effect of fluorine enhances the electrophilic reactivity of the acyl chloride, making acylation efficient, while the steric bulk of the ortho fluorine moderately buffers the reaction rate, reducing side reactions. This combination of “reactivity with controllability” makes it a preferred reagent for fluorinated acylation of substrates bearing sensitive groups, and the fluorine label also confers good metabolic stability on the product.
Applications: Intermediate for fluorinated antipsychotic, anti-inflammatory and cardiovascular drugs; fluorinated herbicides, insecticides and liquid crystal display materials.
|
Appearance |
Colorless transparent liquid |
|
Melting Point |
4 °C |
|
Boiling Point |
95 °C / 20 mmHg |
|
Molecular Formula |
C7H4ClFO |
|
Molecular Weight |
158.56 g/mol |
|
Purity |
≥ 99% |
|
Packaging |
250 kg drum |
|
COA |
Available on request |
MOQ varies by product. For most intermediates our MOQ starts from 25 kg (one bag/drum). Sample quantities are also available for quality evaluation. Bulk Wholesale 2-Fluorobenzoyl Chloride CAS 393-52-2.
Yes, small samples (50–100 g) are generally free of charge; the courier freight is collect or paid by the buyer. For some high-value products a sample fee may apply, which is refundable upon bulk order.
Yes. Every batch is tested in our QC laboratory and a COA is provided with each shipment. Third-party inspection (SGS etc.) is also welcome before loading.
For ready-stock items, 3–7 working days after payment. For large or custom-synthesis orders, typically 15–30 days depending on quantity and process.
Standard export packaging: 25 kg fiber drums / bags, 200 kg HDPE or iron drums. Customized packaging and labeling are available on request. 2-Fluorobenzoyl Chloride Factory Direct
We support FOB, CFR, CIF, DAP and EXW. We have stable partnerships with freight forwarders for sea, air and express delivery.
Yes. With four production bases and 26 years of process experience, we offer custom synthesis from gram scale to ton scale, supported by our R&D technical center. 2-Fluorobenzoyl Chloride Manufacturers in China.
T/T (bank transfer), L/C at sight, and other terms negotiable for long-term partners.